Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8093484 | 0.91 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL8081160 | 0.86 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8129171 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL8088520 | 0.86 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL8089376 | 0.84 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL8088541 | 0.83 | AGTR2 (0.61) | AGTR1AGTR2 | |
| SCHEMBL9195616 | 0.83 | AGTR1 (0.80) | AGTR1AGTR2 | |
| SCHEMBL8707896 | 0.82 | AGTR1 (0.49) | AGTR1AGTR2 | |
| SCHEMBL9844182 | 0.81 | AGTR1 (0.56) | AGTR1AGTR2 | |
| SCHEMBL9850563 | 0.81 | AGTR1 (0.61) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037349-A | HAVING ANTAGONISTIC PROPERTIES TOWARDS ANGIOTENSIN II CAN BE USED FOR THE TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| US-5798364-A | ANGIOTENSIN II ANTAGONIST, USEFUL FOR TREATMENT OF HYPERTENSION, ALDOSTERONISM AND CARDIAC INSUFFICIENCY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-08-25 | — | — | US | disclosed |