Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.36 |
| ▸ | TNKS | O95271 | 1/20 | 0.36 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29278498 | 0.65 | HPGD (0.48) | HPGDTNKS2TNKSPARP3TYR | |
| SCHEMBL7102205 | 0.62 | RAB9A (0.63) | HPGDTNKS2TNKSPARP3LMNA | |
| SCHEMBL13454092 | 0.62 | MAPT (0.57) | HPGDTNKS2TNKSPARP3TYR | |
| SCHEMBL104124 | 0.62 | TYR (0.58) | HPGDTYRMGLLALDH1A1LMNA | |
| SCHEMBL11657580 | 0.60 | — | — | |
| SCHEMBL28912214 | 0.59 | TYR (0.55) | HPGDTYRMGLLALDH1A1LMNA | |
| Ammonia Solution, Strong SCHEMBL7550588 | 0.59 | TYR (0.55) | HPGDTYRMGLLALDH1A1LMNA | |
| Water SCHEMBL29278796 | 0.59 | TYR (0.55) | HPGDTYRMGLLALDH1A1LMNA | |
| SCHEMBL6203905 | 0.59 | TYR (0.55) | HPGDTYRMGLLALDH1A1LMNA | |
| Water SCHEMBL11726962 | 0.59 | TYR (0.55) | HPGDTYRMGLLALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051394-A1 | POTASSIUM CHANNEL INHIBITORS | Icagen, Inc. (US) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037607-A1 | POTASSIUM CHANNEL INHIBITORS | ICAGEN, INC. (US) | 1999-07-29 | — | — | WO | disclosed |