Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.63 |
| ▸ | MEN1 | O00255 | 4/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | TP53 | P04637 | 3/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HTR2B | P41595 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.53 |
| ▸ | TNKS | O95271 | 1/20 | 0.53 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525348 | 0.79 | MAPT (0.71) | RAB9AMEN1KMT2AMAPTTP53 | |
| Clorindione SCHEMBL43305 | 0.78 | RAB9A (1.00) | RAB9AMEN1KMT2AMAPTTP53 | |
| SCHEMBL10559578 | 0.78 | MEN1 (1.00) | RAB9AMEN1KMT2AMAPTTP53 | |
| Phenindione SCHEMBL33831 | 0.77 | MAPT (1.00) | RAB9AMEN1KMT2AMAPTTP53 | |
| Phenindione SCHEMBL29388073 | 0.77 | MAPT (1.00) | RAB9AMEN1KMT2AMAPTTP53 | |
| SCHEMBL10559114 | 0.74 | MAPT (0.95) | RAB9AMEN1KMT2AMAPTTP53 | |
| Phenindione SCHEMBL1443973 | 0.74 | MAPT (0.95) | RAB9AMEN1KMT2AMAPTTP53 | |
| Phenindione SCHEMBL6827577 | 0.74 | MAPT (0.95) | RAB9AMEN1KMT2AMAPTTP53 | |
| SCHEMBL5649473 | 0.74 | KMT2A (1.00) | RAB9AMEN1KMT2AMAPTTP53 | |
| Bromindione SCHEMBL29369456 | 0.74 | KMT2A (1.00) | RAB9AMEN1KMT2AMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764886-B1 | Electrophotosensitive material containing a naphthoquinone derivative | KYOCERA MITA CORP (JP) | 2003-09-03 | — | — | EP | disclosed |
| US-5994012-A | CHARGE GENERATING COMPOUND, CHARGE TRANSFER COMPOUND AND BINDER | MITA INDUSTRIAL CO., LTD. (JP) | 1999-11-30 | — | — | US | disclosed |
| US-5863688-A | REACTING 1,3-INDANDIONE DERIVATIVE WITH A BROMOACETIC ESTER TO FORM 1,3-INDANDIONE ESTER, ISOMERIZING THE ESTER DERIVATIVE IN PRESENCE OF SODIUM HYDRIDE TO FORM NAPHTHOIC ESTER, OXIDIZING TO FORM NAPHTHOQUINONE DERIVATIVE | MITA INDUSTRIAL CO., LTD (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0879811-A1 | Naphthoquinone derivatives and electro-photosensitive material using same | MITA INDUSTRIAL CO. LTD. (JP) | 1998-11-25 | — | — | EP | disclosed |
| EP-0764886-A2 | Naphthoquinone derivative and electrophotosensitive material using the same | MITA INDUSTRIAL CO. LTD. (JP) | 1997-03-26 | — | — | EP | disclosed |