Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.37 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14152473 | 0.88 | KDM4E (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14152475 | 0.88 | KDM4E (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL14152474 | 0.88 | KDM4E (0.40) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL20925006 | 0.87 | HTT (0.55) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL5016815 | 0.85 | EPHX2 (0.41) | ALDH1A1NPSR1CA12CA1CA9 | |
| SCHEMBL5016813 | 0.85 | EPHX2 (0.41) | ALDH1A1NPSR1CA12CA1CA9 | |
| SCHEMBL5016808 | 0.85 | EPHX2 (0.41) | ALDH1A1NPSR1CA12CA1CA9 | |
| SCHEMBL29037327 | 0.84 | TRPA1 (0.39) | ALDH1A1MAPTCA12CA1CA9 | |
| SCHEMBL28977277 | 0.84 | MAPT (0.53) | ALDH1A1CES2CES1MAPTMEN1 | |
| SCHEMBL8090077 | 0.82 | LMNA (0.50) | ALDH1A1CES2CES1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048896-A | FOR TREATMENT OF BRAIN OR NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-04-11 | — | — | US | disclosed |