Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.74 |
| ▸ | POLB | P06746 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | HPGD | P15428 | 2/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.62 |
| ▸ | MAPT | P10636 | 3/20 | 0.62 |
| ▸ | TP53 | P04637 | 1/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | STAT3 | P40763 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28335090 | 0.85 | MEN1 (1.00) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11679178 | 0.85 | MEN1 (0.77) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL4007599 | 0.84 | MEN1 (0.74) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL13741334 | 0.81 | KMT2A (0.70) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11820160 | 0.81 | MEN1 (0.70) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL11644158 | 0.80 | MEN1 (0.68) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL13741525 | 0.80 | MEN1 (0.68) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL5208634 | 0.80 | MAPT (0.70) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL17084253 | 0.80 | MEN1 (0.87) | MEN1KMT2APOLBALDH1A1HPGD | |
| SCHEMBL4888533 | 0.80 | MAPT (0.75) | MEN1KMT2APOLBALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0672038-B1 | HERBICIDES | ZENECA LTD (GB) | 2000-01-19 | — | — | EP | disclosed |
| US-5856273-A | CONTROLLING WEEDS | ZENECA LIMITED (GB) | 1999-01-05 | — | — | US | disclosed |
| EP-0672038-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1995-09-20 | — | — | EP | disclosed |
| WO-1994013652-A1 | HERBICIDES | ZENECA LIMITED (GB) | 1994-06-23 | — | — | WO | disclosed |