Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.42 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379412 | 0.83 | PRSS1 (0.36) | SMPD1 | |
| SCHEMBL1637027 | 0.82 | NQO1 (0.44) | TSHRLTA4HTP53 | |
| SCHEMBL677235 | 0.81 | TSHR (0.47) | TSHRNR5A1SMPD1LTA4HPLA2G2A | |
| SCHEMBL27688593 | 0.81 | FBP1 (0.35) | — | |
| SCHEMBL2092766 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1LTA4HPLA2G2A | |
| SCHEMBL1664744 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1LTA4HPLA2G2A | |
| SCHEMBL20819716 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1LTA4HPLA2G2A | |
| SCHEMBL20819713 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1LTA4HPLA2G2A | |
| SCHEMBL1669927 | 0.79 | TSHR (0.50) | TSHRNR5A1SMPD1LTA4HTHRA | |
| SCHEMBL920839 | 0.79 | TSHR (0.46) | TSHRNR5A1SMPD1LTA4HPLA2G2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1053247-A1 | ANTIFUNGAL CYCLOHEXAPEPTIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-22 | — | — | EP | disclosed |
| WO-1999040108-A1 | NEW COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-08-12 | — | — | WO | disclosed |