Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BUB1 | O43683 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786132 | 0.77 | SMN1; SMN2 (0.55) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL13006980 | 0.76 | TSHR (0.41) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL3212086 | 0.76 | TSHR (0.41) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL29866208 | 0.76 | TSHR (0.41) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL13897208 | 0.76 | SLC6A3 (0.48) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL4946908 | 0.76 | TSHR (0.41) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL855229 | 0.76 | CHRNA1 (0.48) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL5339706 | 0.76 | OPRD1 (0.49) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL12823209 | 0.76 | TSHR (0.41) | TSHRSMN1; SMN2LMNAMAPTGAA | |
| SCHEMBL29841314 | 0.76 | TSHR (0.41) | TSHRSMN1; SMN2LMNAMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096895-A | Heterocyclic dihydrazole compounds and their use for controlling fungal plant diseases | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2000-08-01 | — | — | US | disclosed |
| EP-0825992-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1998-03-04 | — | — | EP | disclosed |
| WO-1996036633-A1 | FUNGICIDAL CYCLIC AMIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-11-21 | — | — | WO | disclosed |