Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8079176 | 0.82 | LRRK2 (0.32) | GAAEPHX2LRRK2 | |
| SCHEMBL8087588 | 0.71 | PRMT5 (0.31) | — | |
| SCHEMBL8087600 | 0.70 | GAA (0.34) | GAA | |
| SCHEMBL22890673 | 0.67 | HSD17B10 (0.48) | GAA | |
| SCHEMBL15554853 | 0.65 | — | — | |
| SCHEMBL12000340 | 0.65 | — | — | |
| SCHEMBL6652064 | 0.62 | GAA (0.56) | GAA | |
| SCHEMBL12050434 | 0.61 | EPHX2 (0.33) | EPHX2 | |
| SCHEMBL7401096 | 0.61 | HCAR2 (0.31) | — | |
| SCHEMBL11526298 | 0.60 | LMNA (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051431-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999037668-A1 | THROMBIN INHIBITORS | BASF AKTIENGESELLSCHAFT (DE) | 1999-07-29 | — | — | WO | disclosed |