Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 10/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 7/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.52 |
| ▸ | HTR2B | P41595 | 1/20 | 0.52 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3914192 | 1.00 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AHTR2CTMIGD3 | |
| SCHEMBL3914182 | 1.00 | ADORA3 (0.58) | ADORA3ADORA1ADORA2AHTR2CTMIGD3 | |
| Formic Acid SCHEMBL6574660 | 0.90 | ADORA2A (0.53) | ADORA3ADORA1ADORA2AHTR2CTMIGD3 | |
| SCHEMBL2809155 | 0.88 | ADORA1 (0.70) | ADORA3ADORA1ADORA2AHTR2CADORA2B | |
| SCHEMBL4230273 | 0.88 | ADORA1 (0.70) | ADORA3ADORA1ADORA2AHTR2CADORA2B | |
| SCHEMBL3913337 | 0.88 | ADORA1 (0.70) | ADORA3ADORA1ADORA2AHTR2CADORA2B | |
| SCHEMBL2832621 | 0.88 | ADORA1 (0.70) | ADORA3ADORA1ADORA2AHTR2CADORA2B | |
| SCHEMBL6839103 | 0.88 | ADORA3 (0.54) | ADORA3ADORA1ADORA2AHTR2CTMIGD3 | |
| Trifluoroacetic Acid SCHEMBL6839083 | 0.88 | ADORA1 (0.51) | ADORA3ADORA1ADORA2AHTR2CTMIGD3 | |
| SCHEMBL6574586 | 0.86 | ADORA3 (0.52) | ADORA3ADORA1ADORA2AADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1051425-A2 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-11-15 | — | — | EP | disclosed |
| WO-1999038877-A2 | 2-(PURIN-9-yl)-TETRAHYDROFURAN-3,4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-08-05 | — | — | WO | disclosed |