Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 9/20 | 0.53 |
| ▸ | ADORA1 | P30542 | 8/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 8/20 | 0.53 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6574661 | 0.90 | ADORA1 (0.48) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| SCHEMBL6574664 | 0.90 | ADORA1 (0.48) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| SCHEMBL3914192 | 0.90 | ADORA3 (0.58) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| SCHEMBL3914182 | 0.90 | ADORA3 (0.58) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| SCHEMBL8090571 | 0.90 | ADORA3 (0.58) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| Trifluoroacetic Acid SCHEMBL6839083 | 0.84 | ADORA1 (0.51) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| Formic Acid SCHEMBL6576731 | 0.84 | ADORA3 (0.51) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| SCHEMBL6839103 | 0.83 | ADORA3 (0.54) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| Formic Acid SCHEMBL6574863 | 0.82 | ADORA1 (0.52) | ADORA2AADORA1ADORA3HTR2CTMIGD3 | |
| Formic Acid SCHEMBL6838965 | 0.81 | ADORA2A (0.49) | ADORA2AADORA1ADORA3ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1090019-B1 | ADENOSINE DERIVATIVES | GLAXO GROUP LTD (GB) | 2004-09-29 | — | — | EP | disclosed |
| EP-1447407-A1 | Adenosine derivatives | GLAXO GROUP LIMITED (GB) | 2004-08-18 | — | — | EP | disclosed |