Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 2/20 | 0.47 |
| ▸ | CDK2 | P24941 | 2/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | FPR1 | P21462 | 1/20 | 0.43 |
| ▸ | FPR2 | P25090 | 1/20 | 0.43 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 3/20 | 0.39 |
| ▸ | MET | P08581 | 2/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
| ▸ | LTK | P29376 | 1/20 | 0.39 |
| ▸ | GRK5 | P34947 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.39 |
| ▸ | MST1R | Q04912 | 1/20 | 0.39 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16652420 | 0.78 | CCNE1 (0.47) | CCNE1CDK2PARP1ALDH1A1FPR1 | |
| SCHEMBL15978138 | 0.73 | FPR1 (0.51) | CCNE1CDK2PARP1ALDH1A1FPR1 | |
| SCHEMBL11304106 | 0.68 | NPC1 (0.56) | CCNE1CDK2PARP1ALDH1A1RET | |
| SCHEMBL23402400 | 0.65 | MEN1 (0.47) | PARP1ALDH1A1MEN1GAAKMT2A | |
| SCHEMBL4208272 | 0.64 | PARP1 (1.00) | CDK2PARP1ALDH1A1CLK4CDK8 | |
| SCHEMBL564994 | 0.64 | GAA (0.78) | MEN1GAAKMT2ANPC1MAPT | |
| SCHEMBL8987328 | 0.64 | PARP1 (0.48) | CCNE1CDK2PARP1ALDH1A1MEN1 | |
| Phosphine SCHEMBL27556263 | 0.64 | ALDH1A1 (0.58) | ALDH1A1MGLLHDAC4HDAC2HDAC8 | |
| SCHEMBL3485241 | 0.63 | PARP1 (0.47) | CCNE1CDK2PARP1ALDH1A1CLK4 | |
| SCHEMBL21563888 | 0.63 | PARP1 (0.52) | CCNE1CDK2PARP1ALDH1A1CLK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0725641-B1 | NOVEL INHIBITORS OF URIDINE PHOSPHORYLASE (UrdPase) AND DIHYDROURACIL DEHYDROGENASE (DHUDase) | EL KOUNI MAHMOUD H (US) | 2000-12-13 | — | — | EP | claimed |