SCHEMBL8090735

SCHEMBL8090735

O=Cc1cccc(O)c1-c1ccc(O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 6/20 0.53
TRIM24 O15164 1/20 0.52
TRIM33 Q9UPN9 1/20 0.52
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
BACE1 P56817 1/20 0.42
APP P05067 1/20 0.40
ALDH5A1 P51649 1/20 0.40
ABAT P80404 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LMNA P02545 1/20 0.39
THRB P10828 1/20 0.39
BLM P54132 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
ESR1 P03372 4/20 0.39
ESR2 Q92731 3/20 0.38
TLR2 O60603 1/20 0.38
TLR1 Q15399 1/20 0.38
TLR6 Q9Y2C9 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6267216 0.86 TRIM24 (0.59) ERN1TRIM24TRIM33CA1CA2
SCHEMBL7932613 0.85 ERN1 (0.50) ERN1TRIM24TRIM33CA1CA2
SCHEMBL16432178 0.85 ERN1 (0.50) ERN1TRIM24TRIM33CA1CA2
SCHEMBL6048616 0.83 ERN1 (0.67) ERN1TRIM24TRIM33CA1CA2
SCHEMBL8926741 0.81 MEN1 (0.41) ERN1TRIM24TRIM33CA1CA2
SCHEMBL8936342 0.79 ESR1 (0.53) CA1CA2BACE1APPMEN1
Salicyladehyde SCHEMBL28950379 0.77 TRIM24 (0.86) ERN1TRIM24TRIM33CA1CA2
SCHEMBL27271196 0.76 ERN1 (0.61) ERN1BACE1MEN1KMT2ATDP1
SCHEMBL18529813 0.75 ERN1 (0.49) ERN1TRIM24TRIM33CA1CA2
Hydroquinone SCHEMBL28407198 0.74 ERN1 (0.55) ERN1TRIM24TRIM33CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0637613-B1 RESIN COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2000-10-25 EP disclosed
US-5543474-A BLEND OF A AROMATIC POLYAMIDEIMIDE COPOLYMER AND A POLYESTER MITSUBISHI GAS COMPANY, INC. (JP) 1996-08-06 US disclosed
EP-0637613-A1 RESIN COMPOSITION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 1995-02-08 EP disclosed