SCHEMBL8926741

SCHEMBL8926741

O=Cc1cccc(Cl)c1-c1ccc(O)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
HSP90AA1 P07900 1/20 0.41
MAPT P10636 1/20 0.41
ERN1 O75460 7/20 0.41
TDP1 Q9NUW8 2/20 0.41
ALDH1A1 P00352 1/20 0.41
TRIM24 O15164 1/20 0.39
TRIM33 Q9UPN9 1/20 0.39
YES1 P07947 1/20 0.39
EPHB4 P54760 1/20 0.39
MAOA P21397 1/20 0.39
ALDH5A1 P51649 1/20 0.38
ABAT P80404 1/20 0.38
LMNA P02545 1/20 0.37
THRB P10828 1/20 0.37
BLM P54132 1/20 0.37
ESR1 P03372 3/20 0.36
ESR2 Q92731 1/20 0.36
TLR2 O60603 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3348634 0.83 KMT2A (0.46) MEN1KMT2AMAPTTDP1ALDH1A1
SCHEMBL8090735 0.81 ERN1 (0.53) MEN1KMT2AERN1TDP1TRIM24
SCHEMBL28066782 0.80 ESR1 (0.48) MEN1KMT2AMAPTALDH1A1YES1
SCHEMBL14877176 0.80 ALDH1A1 (0.54) MEN1KMT2AERN1TDP1ALDH1A1
SCHEMBL14270107 0.74 ESR1 (0.44) ERN1ALDH5A1ABATESR1ESR2
SCHEMBL6058772 0.73 ERN1 (0.39) ERN1TRIM24TRIM33THRBESR1
SCHEMBL27271196 0.73 ERN1 (0.61) MEN1KMT2AMAPTERN1TDP1
SCHEMBL359233 0.72 ERN1 (0.61) MEN1KMT2AMAPTERN1TDP1
SCHEMBL29952063 0.72 ERN1 (0.61) MEN1KMT2AMAPTERN1TDP1
SCHEMBL6535649 0.72 TDP1 (0.46) MEN1KMT2AERN1TDP1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5681689-A COUPLING WITH OXIDIZED COLOR DEVELOPER EASTMAN KODAK COMPANY (US) 1997-10-28 US disclosed