SCHEMBL8936342

SCHEMBL8936342

Oc1ccc(-c2c(O)cccc2O)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 6/20 0.53
ESR2 Q92731 5/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
APP P05067 2/20 0.50
MMP3 P08254 1/20 0.50
BCL2L1 Q07817 1/20 0.50
BACE1 P56817 1/20 0.48
HSD17B1 P14061 2/20 0.48
HSD17B2 P37059 2/20 0.48
ALDH1A1 P00352 3/20 0.48
HPGD P15428 3/20 0.48
HSD17B10 Q99714 3/20 0.48
MAPT P10636 2/20 0.48
SENP1 Q9P0U3 1/20 0.48
POLB P06746 1/20 0.48
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
LMNA P02545 2/20 0.44
ALOX15 P16050 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28312144 0.85 BACE1 (0.51) ESR1ESR2MEN1KMT2AAPP
SCHEMBL2936698 0.84 ALOX15 (0.46) ESR1ESR2MEN1KMT2AAPP
Hydrochloric Acid SCHEMBL2938598 0.82 ALOX15 (0.44) ESR1ESR2MEN1KMT2AAPP
SCHEMBL8090728 0.80 LIG1 (0.50) ESR1ESR2MEN1KMT2AAPP
SCHEMBL355552 0.80 ALDH1A1 (0.55) ESR1ESR2MMP3BCL2L1BACE1
SCHEMBL29034039 0.80 ALDH1A1 (0.50) ESR1ESR2MEN1KMT2AAPP
SCHEMBL17411324 0.79 ALDH1A1 (0.46) ESR1ESR2BACE1ALDH1A1HPGD
SCHEMBL7785632 0.79 ACHE (0.43) MEN1KMT2AALDH1A1HPGDHSD17B10
SCHEMBL27522728 0.79 ALOX5 (0.48) ESR2MEN1KMT2AHSD17B1HSD17B2
SCHEMBL27864721 0.79 AR (0.43) ESR2MEN1KMT2ABCL2L1HSD17B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107107389-B Method for producing a densified polymer powder, and method for melt-processing a densified polymer powder 沙特基础工业全球技术有限公司 2020-05-19 CN disclosed
CN-110922733-A Polycarbonate articles and methods of making the same 沙特基础工业全球技术有限公司 2020-03-27 CN disclosed
CN-110746341-A Method for purifying 2-aryl-3, 3-bis (4-hydroxyaryl) phthalimidines and polymers derived therefrom 沙特基础工业全球技术有限公司 2020-02-04 CN disclosed
US-5589493-A FUNGICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-12-31 US disclosed
US-5512059-A DYEING POLYUREHTANE ELASTIC FIBERS INCLUDING CHLORINE-INDUCED DEGRADATION INHIBITORS THAT DO NO ELUTE OUT TOYO BOSEKI KABUSHIKI KAISHA (JP) 1996-04-30 US disclosed
US-5456960-A A multicomponent yarn comprising a polyurethane elastic fiber containing one or more chlorination resistant inhibitors selected from the group consisting of oxides and hydroxides of magnesium, zinc, aluminum and hydrotalcite TOYO BOSEKI KABUSHIHI KAISHA (JP) 1995-10-10 US disclosed
EP-0489395-B1 Dyed mixed knit fabric and method for its manufacture TOYO BOSEKI (JP) 1995-09-27 EP disclosed
US-5330995-A Fungicides BASF AKTIENGESELLSCHAFT (DE) 1994-07-19 US disclosed
EP-0489395-A1 Dyed mixed knit fabric and method for its manufacture Toyo Boseki Kabushiki Kaisha (JP) 1992-06-10 EP disclosed