Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 5/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8651609 | 0.98 | KDM4E (0.47) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL29857954 | 0.85 | MAPT (0.40) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL4594991 | 0.85 | MAPT (0.40) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL19203466 | 0.76 | CA9 (0.59) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL1880170 | 0.75 | DRD2 (0.59) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL29642933 | 0.75 | DRD2 (0.59) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL94057 | 0.75 | MAPT (0.53) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL2062448 | 0.74 | HTR2A (0.38) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL2062046 | 0.74 | RET (0.41) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL2062026 | 0.74 | KDM4E (0.41) | MAPTKDM4EMEN1KMT2AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743849-B1 | USE OF 1,2,3,4-TETRAHYDROQUINOXALINES AS OXIDATION DYE PRECURSORS IN OXIDATION DYES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |