Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3872761 | 0.98 | MAPT (0.52) | MAPTKDM4EMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL3996527 | 0.98 | MAPT (0.52) | MAPTKDM4EMEN1GAAKMT2A | |
| Ethane SCHEMBL11793205 | 0.96 | MAPT (0.50) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL2555941 | 0.92 | DRD2 (0.52) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL29522368 | 0.88 | MAPT (0.50) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL1098919 | 0.88 | MAPT (0.50) | MAPTKDM4EMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL29566172 | 0.86 | MAPT (0.49) | MAPTKDM4EMEN1GAAKMT2A | |
| SCHEMBL2944234 | 0.86 | KDM4E (0.49) | MAPTKDM4EMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL19743521 | 0.86 | MAPT (0.49) | MAPTKDM4EMEN1GAAKMT2A | |
| Hydrochloric Acid SCHEMBL16337538 | 0.86 | MAPT (0.49) | MAPTKDM4EMEN1GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021018445-A1 | OXIDANT-FREE METHOD FOR DYEING KERATIN MATERIAL, COMPRISING THE APPLICATION OF AN ORGANIC C1-C6-ALKOXY SILANE AND AN OXIDANT-FREE DYE PRECURSOR | HENKEL AG & CO. KGAA (DE) | 2021-02-04 | — | — | WO | claimed |
| CN-110669058-A | Tricyclic quinolone carboxylic acid and preparation method thereof | 江西农业大学 | 2020-01-10 | — | — | CN | claimed |
| US-8629289-B2 | Method for the preparation of 1-acetyl-6-amino-3,3-dimethyl-2,3-dihydroindole | AMGEN INC. (US) | 2014-01-14 | — | — | US | claimed |
| US-8585778-B2 | Cationic 6-aminoindolines, dyeing compositions containing them, processes and uses thereof | L'OREAL (FR) | 2013-11-19 | — | — | US | claimed |
| US-20130081213-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | L'OREAL (FR) | 2013-04-04 | — | — | US | claimed |
| EP-2542525-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | L'Oréal (FR) | 2013-01-09 | — | — | EP | claimed |
| US-20120136163-A1 | Method for the Preparation of 1-Acetyl-6-Amino-3,3-Dimethyl-2,3-Dihydroindole | AMGEN INC. (US) | 2012-05-31 | — | — | US | claimed |
| EP-2376448-A2 | IMPROVED METHOD FOR THE PREPARATION OF 1-ACETYL-6-AMINO-3,3-DIMETHYL-2,3-DIHYDROINDOLE | Amgen, Inc (US) | 2011-10-19 | — | — | EP | claimed |
| WO-2011107501-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | L'OREAL (FR) | 2011-09-09 | — | — | WO | claimed |
| EP-2311801-A1 | 6-amino(aza)indane compounds suitable for treating disorders that respond to modulation of the dopamine d3 receptor | Abbott GmbH & Co. KG (DE) | 2011-04-20 | — | — | EP | claimed |
| EP-0575604-A1 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS. | OREAL (FR) | 1993-12-29 | — | — | EP | claimed |
| EP-0575605-A1 | MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT. | OREAL (FR) | 1993-12-29 | — | — | EP | claimed |
| US-5256799-A | Preparation of 6-hydroxyindolines and their use for preparation of novel laser dyes | THE UNITED STATES OF AMERICAS AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1993-10-26 | — | — | US | claimed |
| WO-1993013745-A1 | MINERAL OR ORGANIC PARTICLE BASED PRODUCT COMPRISING AN INDOLINE PRODUCT | L'OREAL (FR) | 1993-07-22 | — | — | WO | claimed |
| WO-1993013744-A1 | INDOLINE PRODUCTS, METHODS FOR PREPARING SAME, AND USE THEREOF IN COSMETICS | L'OREAL (FR) | 1993-07-22 | — | — | WO | claimed |
| EP-0544874-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-06-09 | — | — | EP | claimed |
| US-5190564-A | PROCESS FOR DYEING KERATINOUS FIBRES COMBINING ISATIN OR ITS DERIVATIVES WITH AN AMINOINDOLE OR AN AMINOINDOLINE, AND COMPOSITIONS USED | L'OREAL (FR) | 1993-03-02 | — | — | US | claimed |
| WO-1993000068-A1 | METHOD FOR PREPARING SUBMICRON PARTICLES IN THE PRESENCE OF LIPID VESICLES, AND CORRESPONDING COMPOSITIONS | L'OREAL (FR) | 1993-01-07 | — | — | WO | claimed |
| EP-0497697-A1 | Keratinous fibres dyeing process with isatine associated with an aminoindol or an aminoindoline, and composition therefor | L'OREAL (FR) | 1992-08-05 | — | — | EP | claimed |
| US-4425132-A | HAIR DYES, APPLYING WITHOUT RINSING | L'OREAL (FR) | 1984-01-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120136163-A1 | Method for the Preparation of 1-Acetyl-6-Amino-3,3-Dimethyl-2,3-Dihydroindole | AANAT, INMT, AADAT | MAPT 928/4885KDM4E 1483/4885MEN1 1108/4885 |
| US-20130081213-A1 | CATIONIC 6-AMINOINDOLINES, DYEING COMPOSITIONS CONTAINING THEM, PROCESSES AND USES THEREOF | AADAT, TYR, DDC | MAPT 1560/4885KDM4E 1899/4885MEN1 1026/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.