Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657537 | 0.73 | CREBBP (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL31357070 | 0.73 | CREBBP (0.40) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL12718887 | 0.71 | NOTUM (0.48) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL7659924 | 0.71 | PARP10 (0.39) | KDM4EMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL3744568 | 0.68 | SRC (0.38) | KDM4EMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL10027765 | 0.67 | ALDH1A1 (0.44) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL13036175 | 0.67 | ADRA2A (0.54) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL17319496 | 0.67 | KDM4E (0.32) | KDM4EHSD17B10GAA | |
| SCHEMBL22679489 | 0.67 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CADRA1DADRA1A | |
| SCHEMBL19422031 | 0.66 | KDM4E (0.32) | KDM4EMEN1KMT2AALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0743849-B1 | USE OF 1,2,3,4-TETRAHYDROQUINOXALINES AS OXIDATION DYE PRECURSORS IN OXIDATION DYES | HENKEL KGAA (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-5752984-A | Use of 1,2,3,4-tetrahydroquinoxalines as oxidation dye precursors in oxidative coloring formulations | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1998-05-19 | — | — | US | disclosed |
| EP-0743849-A1 | USE OF 1,2,3,4-TETRAHYDROQUINOXALINES AS OXIDATION DYE PRECURSORS IN OXIDATION DYES | Henkel Kommanditgesellschaft auf Aktien (DE) | 1996-11-27 | — | — | EP | disclosed |
| WO-1995021604-A1 | USE OF 1,2,3,4-TETRAHYDROQUINOXALINES AS OXIDATION DYE PRECURSORS IN OXIDATION DYES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1995-08-17 | — | — | WO | disclosed |