Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAOB | P27338 | 8/20 | 0.51 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085932 | 0.93 | LDHA (0.49) | FFAR1NPC1POLBRAB9ASMN1; SMN2 | |
| SCHEMBL8090970 | 0.91 | MAOB (0.57) | FFAR1MAOB | |
| SCHEMBL8099655 | 0.87 | LDHA (0.48) | FFAR1NPC1POLBRAB9ASMN1; SMN2 | |
| Caloxetic Acid Free Base SCHEMBL8412091 | 0.86 | MAOB (0.43) | POLBSMN1; SMN2MAOB | |
| Caloxetic Acid Free Base SCHEMBL92689 | 0.86 | MAOB (0.43) | POLBSMN1; SMN2MAOB | |
| Caloxetic Acid Free Base SCHEMBL19667948 | 0.85 | MAOB (0.42) | POLBSMN1; SMN2MAOB | |
| Caloxetic Acid Free Base SCHEMBL29375456 | 0.85 | MAOB (0.42) | POLBSMN1; SMN2MAOB | |
| Caloxetic Acid Free Base SCHEMBL19667947 | 0.85 | MAOB (0.42) | POLBSMN1; SMN2MAOB | |
| SCHEMBL8092343 | 0.85 | MAOB (0.41) | FFAR1SMN1; SMN2MAOB | |
| SCHEMBL8099090 | 0.84 | SMN1; SMN2 (0.44) | FFAR1NPC1POLBRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6039931-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | claimed |
| EP-0405704-B1 | DTPA-complexes derivatives, pharmaceutical compositions containing them, their use and process for their preparation | SCHERING AG (DE) | 1994-12-14 | — | — | EP | claimed |
| US-6039931-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5798092-A | METAL COMPLEXES; CONTRAST AGENTS FOR MEDICAL IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-25 | — | — | US | disclosed |