Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.37 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.37 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140038 | 0.94 | MAOB (0.44) | MAOBALOX15ALDH1A1TSHRSMN1; SMN2 | |
| Caloxetic Acid Free Base SCHEMBL92689 | 0.89 | MAOB (0.43) | MAOBALDH1A1SMN1; SMN2 | |
| Caloxetic Acid Free Base SCHEMBL8412091 | 0.89 | MAOB (0.43) | MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL8842428 | 0.89 | ALDH1A1 (0.41) | MAOBKCNH2ALDH1A1MEN1KMT2A | |
| Caloxetic Acid Free Base SCHEMBL19667947 | 0.88 | MAOB (0.42) | MAOBALDH1A1SMN1; SMN2 | |
| Caloxetic Acid Free Base SCHEMBL29375456 | 0.88 | MAOB (0.42) | MAOBALDH1A1SMN1; SMN2 | |
| Caloxetic Acid Free Base SCHEMBL19667948 | 0.88 | MAOB (0.42) | MAOBALDH1A1SMN1; SMN2 | |
| SCHEMBL8092304 | 0.87 | LMNA (0.44) | MAOBKCNH2ALDH1A1TSHR | |
| SCHEMBL8090970 | 0.87 | MAOB (0.57) | MAOBFFAR1 | |
| SCHEMBL8085932 | 0.86 | LDHA (0.49) | MAOBSMN1; SMN2FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6039931-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | claimed |
| US-5695739-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | claimed |
| US-6039931-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 2000-03-21 | — | — | US | disclosed |
| US-5798092-A | METAL COMPLEXES; CONTRAST AGENTS FOR MEDICAL IMAGING | SCHERING AKTIENGESELLSCHAFT (DE) | 1998-08-25 | — | — | US | disclosed |
| US-5695739-A | Derivatized DTPA complexes, pharmaceutical agents containing these compounds, their use, and processes for their production | SCHERING AKTIENGESELLSCHAFT (DE) | 1997-12-09 | — | — | US | disclosed |