Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | APEX1 | P27695 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | MMP9 | P14780 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 3/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8086879 | 0.86 | ALDH1A1 (0.47) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL16254041 | 0.78 | ALDH1A1 (0.47) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL2723561 | 0.77 | ALDH1A1 (0.54) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL3892613 | 0.73 | ALDH1A1 (0.50) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL5529302 | 0.73 | NPC1 (0.47) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL28272496 | 0.73 | ALDH1A1 (0.49) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL8079775 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL8088061 | 0.72 | ALDH1A1 (0.45) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL4878584 | 0.72 | ALDH1A1 (0.49) | ALDH1A1LMNAALOX15APEX1MAPK1 | |
| SCHEMBL19458772 | 0.72 | ESR1 (0.56) | ALDH1A1LMNAMAPK1TDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0862550-B1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AG (DE) | 2000-11-08 | — | — | EP | disclosed |
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |
| EP-0862550-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1998-09-09 | — | — | EP | disclosed |
| WO-1997009294-A1 | CARBOXYLIC ACID DERIVATIVES, THEIR PREPARATION AND THEIR USE | BASF AKTIENGESELLSCHAFT (DE) | 1997-03-13 | — | — | WO | disclosed |