Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 4/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.67 |
| ▸ | MAPT | P10636 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | RAD52 | P43351 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17144905 | 0.81 | ALDH1A1 (0.71) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL1148346 | 0.80 | MAOA (1.00) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL11743358 | 0.79 | MAOA (0.67) | MAOAKDM4EMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL10660329 | 0.79 | MAOA (0.96) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL11742117 | 0.78 | KDM4E (0.61) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL1820002 | 0.77 | CYP1A2 (0.72) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL29868545 | 0.77 | CYP1A2 (0.72) | MAOAKDM4EMAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL11744933 | 0.77 | KDM4E (0.59) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL23747284 | 0.76 | KDM4E (0.63) | MAOAKDM4EMAPTALDH1A1GAA | |
| SCHEMBL8099984 | 0.76 | ALDH1A1 (0.56) | KDM4EMAPTALDH1A1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063789-A | Aminoisoquinolines and aminotheinopyridine derivatives and their use as anti-inflammatory agents | ASTRA PHARMACEUTICALS, LTD. (GB) | 2000-05-16 | — | — | US | disclosed |
| CN-1221407-A | Aminoisoquinolines and aminothienopyridine derivatives and their use as anti-inflammatory agents | ASTRA PHARMA PROD (GB) | 1999-06-30 | — | — | CN | disclosed |
| EP-0892784-A1 | AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | Astra Pharmaceuticals Limited (GB) | 1999-01-27 | — | — | EP | disclosed |
| WO-1997038977-A1 | AMINOISOQUINOLINES AND AMINOTHIENOPYRIDINE DERIVATIVES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-10-23 | — | — | WO | disclosed |
| US-4127720-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-11-28 | — | — | US | disclosed |