Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 2/20 | 0.39 |
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | GUSB | P08236 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8089805 | 0.79 | KCNH2 (0.43) | TOP2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8902318 | 0.77 | KCNH2 (0.52) | TOP1TOP2AALDH1A1KDM4EHPGD | |
| SCHEMBL8902323 | 0.77 | KCNH2 (0.52) | TOP1TOP2AALDH1A1KDM4EHPGD | |
| SCHEMBL8091231 | 0.75 | KDM4E (0.40) | TOP2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8903272 | 0.74 | ALDH1A1 (0.49) | TOP1TOP2AALDH1A1KDM4EHPGD | |
| SCHEMBL8903277 | 0.74 | ALDH1A1 (0.49) | TOP1TOP2AALDH1A1KDM4EHPGD | |
| SCHEMBL8573058 | 0.74 | ALDH1A1 (0.49) | TOP1TOP2AALDH1A1KDM4EHPGD | |
| SCHEMBL8091409 | 0.72 | KDM4E (0.40) | TOP2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8091252 | 0.72 | KCNH2 (0.49) | TOP2AALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL8091158 | 0.71 | KCNH2 (0.54) | TOP2AALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |