Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C2 | P08235 | 4/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.47 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 3/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8509173 | 0.91 | CYP2C9 (0.55) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL4447494 | 0.91 | CYP2C9 (0.55) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL30192384 | 0.91 | CYP2C9 (0.55) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8912184 | 0.87 | NR3C2 (0.47) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL9284454 | 0.85 | CYP1A2 (0.53) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL8021648 | 0.84 | CYP2C9 (0.56) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL11110139 | 0.82 | NR3C2 (0.48) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11106245 | 0.82 | CACNA1B (0.60) | CYP2C9CYP1A2CYP3A4CYP2C19MEN1 | |
| SCHEMBL6947811 | 0.81 | CYP1A2 (0.56) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 | |
| SCHEMBL11131329 | 0.81 | CACNA1C (0.44) | NR3C2CYP2C9CYP1A2CYP3A4CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066655-A | FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, IN PARTICULAR AS CEREBRAL THERAPEUTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| US-5731333-A | LEARNING AND MEMORY ENHANCEMENT, ANTIDEPRESSANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |