Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.51 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.44 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.44 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9048399 | 0.91 | KDM4E (0.43) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8092868 | 0.88 | KDM4E (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8091136 | 0.87 | KCNH2 (0.46) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8083142 | 0.86 | DPP4 (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8094753 | 0.85 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8090947 | 0.81 | KDM4E (0.57) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8097813 | 0.80 | KDM4E (0.59) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9045946 | 0.80 | DPP4 (0.43) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9045493 | 0.80 | KDM4E (0.44) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL9047130 | 0.79 | ADRB2 (0.39) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6018054-A | INTERMEDIATE COMPOUNDS FOR PREPARING NOVEL QUINOLONE AND NAPHTHYRIDONE DERIVATIVES WHICH ARE SUBSTITUTED IN THE 7-POSITION BY A PARTIALLY HYDROGENATED ISOINDOLINYL RING, USE AS ANTIBACTERIAL AGENTS AND AS FEED ADDITIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2000-01-25 | — | — | US | disclosed |
| US-5556979-A | ANIMAL FEEDS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-09-17 | — | — | US | disclosed |