Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.37 |
| ▸ | RXRB | P28702 | 1/20 | 0.37 |
| ▸ | RXRG | P48443 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12550528 | 0.85 | CYP3A4 (0.44) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11815109 | 0.83 | APEX1 (0.46) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11722664 | 0.82 | APEX1 (0.44) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL10865877 | 0.82 | FSCN1 (0.50) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL2095708 | 0.82 | APEX1 (0.44) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL1324846 | 0.82 | TSHR (0.45) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL3191479 | 0.82 | TSHR (0.50) | ALDH1A1TSHRNR1H4SMN1; SMN2LMNA | |
| SCHEMBL11517542 | 0.82 | APEX1 (0.42) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL11257421 | 0.81 | APEX1 (0.45) | APEX1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL7564060 | 0.81 | ALDH1A1 (0.36) | APEX1GPBAR1ALDH1A1NR1H4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7645903-B2 | immunoglobulins; affinity chromatography | GE HEALTHCARE BIO-SCIENCES AB (SE) | 2010-01-12 | — | — | US | disclosed |
| US-6117821-A | COMPRISING HERBICIDES AND AGRONOMICALLY ACCEPTABLE CARRIERS; USE THEREOF AS BROAD SPECTRUM HERBICIDES WHICH ARE EFFECTIVE AGAINST BOTH MONOCOT AND DICOT WEED SPECIES IN BOTH PREEMERGENCE AND POSTEMERGENCE APPLICATIONS | ROHM AND HAAS COMPANY (US) | 2000-09-12 | — | — | US | disclosed |
| US-6025301-A | BROAD SPECTRUM HERBICIDES EFFECTIVE AGAINST BOTH MONOCOT AND DICOT WEED SPECIES IN POSTEMERGENCE APPLICATIONS | ROHM AND HAAS COMPANY (US) | 2000-02-15 | — | — | US | disclosed |
| US-5883044-A | Herbicidal method utilizing phosphosulfonate herbicides and oxime ether safeners | ROHM AND HAAS COMPANY (US) | 1999-03-16 | — | — | US | disclosed |
| US-5866513-A | Aryl-substituted cycloalkanes and cycloalkenes and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1999-02-02 | — | — | US | disclosed |
| EP-0699390-B1 | Compositions containing phosphosulfonate herbicides and dichloroacetamide safeners, and method of use | ROHM & HAAS (US) | 1998-10-07 | — | — | EP | disclosed |
| EP-0862860-A2 | Indanone herbicide compositions and use thereof | ROHM AND HAAS COMPANY (US) | 1998-09-09 | — | — | EP | disclosed |
| US-5733849-A | Halopyridyl triazolinone herbicides and herbicidal use thereof | ROHM AND HAAS COMPANY (US) | 1998-03-31 | — | — | US | disclosed |
| US-5726124-A | IN MIXTURE WITH OTHER HERBICIDES, ALKYLATION AND ETHERIFICATION OF PYRIMIDINONE AND THIOPYRIMIDINONE COMPOUNDS | ROHM AND HAAS COMPANY (US) | 1998-03-10 | — | — | US | disclosed |
| US-5723414-A | APPLYING TO WEEDS | ROHM AND HAAS COMPANY (US) | 1998-03-03 | — | — | US | disclosed |
| US-4065292-A | N-(3,4-DICHLOROPHENYL)-N',N'-DIMETHYL THIOUREA | BAYER AKTIENGESELLSCHAFT (DT) | 1977-12-27 | — | — | US | disclosed |
| US-4063929-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-12-20 | — | — | US | disclosed |
| US-4059435-A | Herbicidal 4-trifluoromethyl-3-cyanoalkoxy-4-nitro diphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-11-22 | — | — | US | disclosed |
| US-4058525-A | 4-Amino-5-thione-1,2,4-triazines | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-15 | — | — | US | disclosed |
| US-4057418-A | Sulfonylmethylamino-substituted benzoic acids and herbicidal method therewith | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
| US-4046798-A | Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers | ROHM AND HAAS COMPANY (US) | 1977-09-06 | — | — | US | disclosed |
| US-4039588-A | ALKOXY, AMINO, HALO-, OR CYANO-SUBSTITUTED | ROHM AND HAAS COMPANY (US) | 1977-08-02 | — | — | US | disclosed |
| US-3962307-A | HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-06-08 | — | — | US | disclosed |
| US-3954875-A | Benzophenone herbicides | ROHM AND HAAS COMPANY (US) | 1976-05-04 | — | — | US | disclosed |
| US-3950379-A | HERBICIDES | ROHM AND HAAS COMPANY (US) | 1976-04-13 | — | — | US | disclosed |