Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.35 |
| ▸ | PROC | P04070 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 4/20 | 0.33 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.33 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095158 | 0.99 | MMP8 (0.36) | MMP8F2PROCEPHX2TPSAB1 | |
| SCHEMBL8091532 | 0.97 | MMP8 (0.36) | MMP8F2PROCEPHX2TPSAB1 | |
| SCHEMBL8095454 | 0.95 | MMP8 (0.37) | MMP8F2EPHX2TPSAB1MAPT | |
| SCHEMBL8091524 | 0.94 | F2 (0.37) | MMP8F2PROCEPHX2TPSAB1 | |
| SCHEMBL8095146 | 0.93 | F2 (0.37) | MMP8F2PROCEPHX2TPSAB1 | |
| SCHEMBL8095221 | 0.91 | MMP8 (0.41) | MMP8EPHX2L3MBTL1SPHK1 | |
| SCHEMBL8090189 | 0.91 | MMP8 (0.37) | MMP8F2SPHK1 | |
| SCHEMBL8091528 | 0.91 | F2 (0.37) | MMP8F2PROCEPHX2TPSAB1 | |
| SCHEMBL8095448 | 0.89 | MMP8 (0.38) | MMP8F2EPHX2TPSAB1MAPT | |
| SCHEMBL8091670 | 0.88 | MMP8 (0.38) | MMP8MAPTL3MBTL1MMP1ERCC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |