Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 3/20 | 0.37 |
| ▸ | SPHK1 | Q9NYA1 | 5/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | F10 | P00742 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.32 |
| ▸ | TACR3 | P29371 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8095221 | 0.96 | MMP8 (0.41) | MMP8SPHK1CYP2C19F10MME | |
| SCHEMBL8090174 | 0.94 | F2 (0.39) | MMP8SPHK1F2CYP3A4CYP2C19 | |
| SCHEMBL8095286 | 0.93 | NPY4R (0.38) | MMEKDM4E | |
| SCHEMBL8095158 | 0.92 | MMP8 (0.36) | MMP8SPHK1F2 | |
| SCHEMBL8091531 | 0.91 | MMP8 (0.35) | MMP8SPHK1F2 | |
| SCHEMBL8091532 | 0.90 | MMP8 (0.36) | MMP8SPHK1F2 | |
| SCHEMBL8095211 | 0.90 | MMP8 (0.42) | MMP8SPHK1CYP2C19F10MME | |
| SCHEMBL8098074 | 0.90 | EPHX1 (0.35) | EPHX1MEN1KMT2A | |
| SCHEMBL8095467 | 0.89 | CYP3A4 (0.38) | MMP8F2CYP3A4CYP2C19F10 | |
| SCHEMBL8091593 | 0.88 | MTNR1A (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |