Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091585 | 0.94 | SPHK1 (0.31) | SPHK1ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL8090092 | 0.91 | NPY4R (0.31) | ITGB3ITGA2B | |
| SCHEMBL8083531 | 0.88 | NPY1R (0.31) | ITGB3ITGA2B | |
| SCHEMBL8083520 | 0.88 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8091550 | 0.87 | ITGB3 (0.30) | ITGB3ITGA2B | |
| SCHEMBL8098190 | 0.87 | CTSB (0.32) | — | |
| SCHEMBL8095180 | 0.86 | ITGB3 (0.32) | SPHK1ITGB3ITGA2B | |
| SCHEMBL8091406 | 0.85 | ITGB3 (0.33) | ITGB3ITGA2B | |
| SCHEMBL8090090 | 0.85 | NPY4R (0.32) | SPHK1ITGB3ITGA2BNPC1RAB9A | |
| SCHEMBL8091500 | 0.83 | NPC1 (0.45) | SPHK1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0792883-B1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2000-12-20 | — | — | EP | disclosed |
| EP-0792883-A1 | Novel derivates of boronic acid, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1997-09-03 | — | — | EP | disclosed |