Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 7/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30949511 | 1.00 | TDP1 (0.44) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL12066584 | 0.84 | TDP1 (0.52) | TDP1ATMTSHRALDH1A1CYP3A4 | |
| SCHEMBL10685212 | 0.83 | CYP1A2 (0.55) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL9699609 | 0.83 | GPR35 (0.55) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL13304834 | 0.82 | ALDH1A1 (0.61) | TDP1HSD17B10TSHRALDH1A1CYP3A4 | |
| SCHEMBL20942956 | 0.81 | CYP1A2 (0.47) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL4748223 | 0.80 | TDP1 (0.54) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL14203410 | 0.80 | TSHR (0.47) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL3293461 | 0.80 | TDP1 (0.41) | TDP1ATMHSD17B10TSHRALDH1A1 | |
| SCHEMBL3296412 | 0.80 | ALDH1A1 (0.47) | TDP1ATMHSD17B10TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147075-A | ANALGESICS; PSYCHOLOGICAL DISORDERS | COCENSYS, INC. (US) | 2000-11-14 | — | — | US | disclosed |