Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 18/20 | 0.67 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8085504 | 1.00 | SLC6A9 (0.67) | SLC6A9SLC6A5GPR139P2RX7 | |
| SCHEMBL13970228 | 0.90 | SLC6A9 (0.55) | SLC6A9SLC6A5 | |
| SCHEMBL8086612 | 0.90 | SLC6A9 (0.55) | SLC6A9SLC6A5 | |
| SCHEMBL8085384 | 0.88 | SLC6A9 (0.69) | SLC6A9 | |
| SCHEMBL13970173 | 0.88 | SLC6A9 (0.69) | SLC6A9 | |
| SCHEMBL13970066 | 0.88 | SLC6A9 (0.69) | SLC6A9 | |
| SCHEMBL8086589 | 0.87 | SLC6A9 (0.52) | SLC6A9SLC6A5 | |
| SCHEMBL8088678 | 0.85 | SLC6A9 (0.48) | SLC6A9SLC6A5 | |
| SCHEMBL13970230 | 0.85 | SLC6A9 (0.58) | SLC6A9SLC6A5 | |
| SCHEMBL13970108 | 0.85 | SLC6A9 (0.48) | SLC6A9SLC6A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009013535-A1 | 2-AZABICYCLO(2.2.2)OCTANE DERIVATIVES AS MODULATORS OF THE GLYCINE TRANSPORTER I RECEPTOR | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | WO | disclosed |