Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 17/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970248 | 0.88 | SLC6A9 (0.53) | SLC6A9ALDH1A1SLC6A5 | |
| SCHEMBL8091759 | 0.87 | SLC6A9 (0.67) | SLC6A9SLC6A5 | |
| SCHEMBL8085504 | 0.87 | SLC6A9 (0.67) | SLC6A9SLC6A5 | |
| SCHEMBL13970230 | 0.86 | SLC6A9 (0.58) | SLC6A9SLC6A5 | |
| SCHEMBL8091646 | 0.86 | SLC6A9 (0.56) | SLC6A9SLC6A5 | |
| SCHEMBL8091798 | 0.85 | SLC6A9 (0.57) | SLC6A9 | |
| SCHEMBL13970228 | 0.83 | SLC6A9 (0.55) | SLC6A9SLC6A5 | |
| SCHEMBL8086612 | 0.83 | SLC6A9 (0.55) | SLC6A9SLC6A5 | |
| SCHEMBL13970163 | 0.82 | SLC6A9 (0.64) | SLC6A9SLC6A5 | |
| SCHEMBL8088678 | 0.82 | SLC6A9 (0.48) | SLC6A9SLC6A5MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090030033-A1 | Novel Compounds 894 | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | US | disclosed |
| WO-2009013535-A1 | 2-AZABICYCLO(2.2.2)OCTANE DERIVATIVES AS MODULATORS OF THE GLYCINE TRANSPORTER I RECEPTOR | ASTRAZENECA AB (SE) | 2009-01-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030033-A1 | Novel Compounds 894 | AZI2, TPMT, AMPD2 | SLC6A9 4382/4885ALDH1A1 1930/4885SLC6A5 3965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.