Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6739890 | 0.82 | — | — | |
| SCHEMBL118899 | 0.82 | — | — | |
| Water SCHEMBL29412656 | 0.78 | — | — | |
| Methylene Chloride SCHEMBL1604482 | 0.77 | HTT (0.30) | — | |
| SCHEMBL5493310 | 0.77 | PIK3CD (0.33) | CA2PIK3CD | |
| Trimethylammonium SCHEMBL25390275 | 0.71 | PIK3CD (0.41) | PIK3CD | |
| Diethylamine SCHEMBL17396366 | 0.70 | TP53 (0.42) | — | |
| SCHEMBL9351980 | 0.70 | CA2 (0.38) | CA2PIK3CD | |
| SCHEMBL908858 | 0.69 | CTSA (0.33) | — | |
| SCHEMBL1009857 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040311-A | TREATING BONE DISORDERS FOR PREVENTING OSTEOPOROSIS OR INHIBITING BONE RESORPTION IN A MAMMAL; TREATING TUMOR GROWTH IN A MAMMAL | MERCK & CO., INC. (US) | 2000-03-21 | — | — | US | disclosed |
| US-5952341-A | VITRONECTIN RECEPTOR ANTAGONISTS FOR INHIBITING BONE RESORPTION, TREATING AND PREVENTING OSTEOPOROSIS, AND INHIBITING RESTENOSIS, DIABETIC RETINOPATHY, TUMOR, MACULAR DEGENERATION, ANGIOGENESIS, ATHEROSCLEROSIS, INFLAMMATION | MERCK & CO., INC. (US) | 1999-09-14 | — | — | US | disclosed |