Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.70 |
| ▸ | DRD3 | P35462 | 10/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.56 |
| ▸ | HTR7 | P34969 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078634 | 0.95 | DRD2 (0.77) | DRD2DRD3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8091851 | 0.95 | DRD2 (0.78) | DRD2DRD3ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL8091846 | 0.87 | DRD2 (0.91) | DRD2DRD3ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL8085463 | 0.83 | DRD2 (0.67) | DRD2DRD3ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8086599 | 0.83 | DRD3 (1.00) | DRD2DRD3HTR1AHTR7SLC6A2 | |
| Hydrochloric Acid SCHEMBL8091842 | 0.82 | DRD2 (0.66) | DRD2DRD3ALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL8086583 | 0.82 | DRD2 (1.00) | DRD2DRD3ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL8085595 | 0.79 | DRD2 (0.73) | DRD2DRD3ALDH1A1SMN1; SMN2HTR1A | |
| SCHEMBL8086744 | 0.78 | DRD2 (0.62) | DRD2DRD3ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL8085582 | 0.78 | DRD2 (0.74) | DRD2DRD3ALDH1A1SMN1; SMN2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6103724-A | EXHIBIT MAINLY ANTIPSYCHOTIC EFFECTS, E.G., SCHIZOPHRENIA, ORGANIC MENTAL DISORDERS, AFFECTIVE DISORDERS, ANXIETY, PERSONALITY DISORDERS; NEUROLEPTIC ACTIVITIY; ATYPICAL ANTIPSYCHOTICS, COGNITION ACTIVATORS, ANTIDEPRESSANTS; | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2000-08-15 | — | — | US | disclosed |