SCHEMBL8091848

SCHEMBL8091848

[CH2]Cc1cc(C)c(O)c(C(C)(C)C)c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 4/20 0.57
CYP2C19 P33261 4/20 0.57
CYP1A2 P05177 3/20 0.57
ALDH1A1 P00352 8/20 0.47
TSHR P16473 3/20 0.47
LMNA P02545 2/20 0.47
GAA P10253 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
CA2 P00918 2/20 0.47
POLB P06746 1/20 0.47
TYR P14679 1/20 0.47
HIF1A Q16665 4/20 0.46
MAPK1 P28482 3/20 0.46
MEN1 O00255 2/20 0.46
CYP3A4 P08684 2/20 0.46
BLM P54132 2/20 0.46
KMT2A Q03164 2/20 0.46
ATM Q13315 2/20 0.46
NPSR1 Q6W5P4 2/20 0.46
GMNN O75496 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4447310 0.88 ALDH1A1 (0.59) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL2048054 0.85 CYP1A2 (0.53) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL9850923 0.85 CYP2C9 (0.57) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL39353 0.84 CYP2C9 (0.61) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL29357192 0.84 CYP2C9 (0.61) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL8854338 0.84 CYP1A2 (0.61) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL30008257 0.84 CYP1A2 (0.61) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL8553511 0.82 CYP2C9 (0.59) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL1785592 0.82 CYP2C9 (0.59) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR
SCHEMBL9413678 0.82 CYP2C9 (0.59) CYP2C9CYP2C19CYP1A2ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6046261-A STABILIZER FOR ORGANIC MATERIAL HAVING EXCELLENT BLOOMING RESISTANCE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2000-04-04 US disclosed
US-5473001-A Heat and oxidation resistance; photostability ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-12-05 US disclosed
US-5424349-A Tertiary amides with low volatility and good thermal stability ALBEMARLE CORPORATION (US) 1995-06-13 US disclosed
US-5408008-A Piperidinyl phthalimide hindered amine light stabilizers ELF ATOCHEM NORTH AMERICA, INC. (US) 1995-04-18 US disclosed
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5352719-A Blended with synthetic or natural polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-10-04 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
US-5319090-A Benzotriazole and oxanilide UV absorber hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-06-07 US disclosed
EP-0593936-A1 N-[2-hydroxy-3-(2H-benzotriazol-2-yl)benzyl]oxamides as light stabilisers ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-04-27 EP disclosed
US-5292956-A For lubricants, mineral oils, polypropylene ETHYL CORPORATION (US) 1994-03-08 US disclosed
EP-0494639-A2 Hindered amine light stabilizer hydrazides for stabilizing polyurethane, polyurea and polyurethane-polyurea polymers ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-07-15 EP disclosed
US-5116976-A HINDERED AMINE LIGHT STABILIZER HYDRAZIDES ATOCHEM NORTH AMERICA, INC (US) 1992-05-26 US disclosed
US-5103054-A Polymer antioxidant ETHYL CORPORATION (US) 1992-04-07 US disclosed
EP-0467344-A1 Hindered amine light stabilizer hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1992-01-22 EP disclosed
EP-0409840-A4 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES 1991-09-04 EP disclosed
US-5041545-A 2-hydroxybenzophenone hydrazides and derivatives thereof ATOCHEM NORTH AMERICA, INC. (US) 1991-08-20 US disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed
EP-0409840-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-01-30 EP disclosed
US-4980420-A Benzotriazole and oxanilide UV absorber hydrazides ATOCHEM NORTH AMERICA, INC. (US) 1990-12-25 US disclosed
WO-1990009369-A1 BENZOTRIAZOLE AND OXANILIDE UV ABSORBER HYDRAZIDES ATOCHEM NORTH AMERICA, INC. (US) 1990-08-23 WO disclosed