Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8091657 | 0.84 | SIGMAR1 (0.65) | SIGMAR1KCNH2 | |
| SCHEMBL8084280 | 0.84 | SIGMAR1 (0.57) | SIGMAR1 | |
| SCHEMBL8100041 | 0.82 | SIGMAR1 (0.62) | SIGMAR1KCNH2 | |
| SCHEMBL8084153 | 0.81 | SIGMAR1 (0.59) | SIGMAR1KCNH2 | |
| Hydrochloric Acid SCHEMBL7869157 | 0.77 | SIGMAR1 (0.64) | SIGMAR1KCNH2 | |
| SCHEMBL7369457 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL8091327 | 0.76 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9380377 | 0.75 | SIGMAR1 (0.47) | SIGMAR1 | |
| SCHEMBL8092963 | 0.75 | SIGMAR1 (0.59) | SIGMAR1KCNH2 | |
| SCHEMBL8084143 | 0.74 | SIGMAR1 (1.00) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057371-A | TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, GASTROINTESTINAL DISORDERS, DRUG ABUSE, ANGINA, MIGRAINE, HYPERTENSION AND DEPRESSION | VIRGINIA COMMONWEALTH UNIVERSITY (US) | 2000-05-02 | — | — | US | claimed |