Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064833 | 0.85 | KDR (0.40) | RET | |
| SCHEMBL4064842 | 0.85 | KDR (0.40) | RET | |
| SCHEMBL8090796 | 0.84 | RET (0.34) | RETDGAT2 | |
| SCHEMBL8082699 | 0.78 | CYP1A2 (0.33) | DGAT2 | |
| SCHEMBL30628346 | 0.74 | KDR (0.47) | RET | |
| SCHEMBL31249530 | 0.73 | KDR (0.36) | RET | |
| SCHEMBL31249566 | 0.73 | KDR (0.36) | RET | |
| SCHEMBL30585616 | 0.71 | KDR (0.57) | RETDGAT2 | |
| SCHEMBL13446211 | 0.71 | KDR (0.57) | RETDGAT2 | |
| SCHEMBL18186761 | 0.71 | KDR (0.57) | RETDGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036066-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |