Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8082699 | 0.85 | CYP1A2 (0.33) | DGAT2 | |
| SCHEMBL8092372 | 0.84 | RET (0.31) | RETDGAT2 | |
| SCHEMBL4053575 | 0.80 | RET (0.37) | RETDGAT2 | |
| SCHEMBL4053570 | 0.80 | RET (0.37) | RETDGAT2 | |
| SCHEMBL5207821 | 0.77 | RET (0.39) | RETDGAT2 | |
| SCHEMBL14527956 | 0.76 | GAA (0.34) | RETDGAT2 | |
| SCHEMBL5208307 | 0.76 | GAA (0.34) | RETDGAT2 | |
| SCHEMBL29659128 | 0.73 | GAA (0.47) | RETDGAT2 | |
| SCHEMBL2144073 | 0.73 | GAA (0.47) | RETDGAT2 | |
| SCHEMBL30786116 | 0.72 | RXRA (0.33) | RET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009036066-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
| WO-2008033747-A9 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS INC (MA) | 2008-07-24 | — | — | WO | disclosed |
| WO-2008033747-A2 | MULTI-FUNCTIONAL SMALL MOLECULES AS ANTI-PROLIFERATIVE AGENTS | CURIS, INC. (US) | 2008-03-20 | — | — | WO | disclosed |