Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | CTSG | P08311 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28351448 | 0.81 | POLB (0.45) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL9185214 | 0.77 | GAA (0.41) | ALDH1A1POLBL3MBTL1MAPTELANE | |
| SCHEMBL9601913 | 0.74 | ALDH1A1 (0.39) | ALDH1A1POLBL3MBTL1TLR4MAPT | |
| SCHEMBL10676472 | 0.73 | L3MBTL1 (0.40) | ALDH1A1POLBL3MBTL1MAPTELANE | |
| Acetic Acid SCHEMBL11305411 | 0.73 | CYP2D6 (0.38) | ALDH1A1POLBL3MBTL1ELANECTSG | |
| SCHEMBL11305406 | 0.73 | POLB (0.46) | ALDH1A1POLBMAPTGAAKMT2A | |
| SCHEMBL10499729 | 0.71 | ALDH1A1 (0.37) | ALDH1A1POLBL3MBTL1TLR4MAPT | |
| SCHEMBL30872362 | 0.71 | SMN1; SMN2 (0.41) | ALDH1A1POLBL3MBTL1MAPTKMT2A | |
| SCHEMBL4449589 | 0.70 | TLR4 (0.37) | ALDH1A1POLBTLR4MAPTELANE | |
| SCHEMBL288165 | 0.70 | USP2 (0.50) | ALDH1A1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009037719-A1 | NOVEL COMPOUNDS AS DIPEPTIDYL PEPTIDASE IV (DPP IV) INHIBITORS | LUPIN LIMITED (IN) | 2009-03-26 | — | — | WO | disclosed |