Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.46 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.45 |
| ▸ | THPO | P40225 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | PYGL | P06737 | 2/20 | 0.45 |
| ▸ | PYGM | P11217 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8084731 | 0.86 | CACNA1C (0.46) | ALOX15KDM4EHSD17B10CACNA1BCASP1 | |
| SCHEMBL29991155 | 0.86 | CYP2C9 (0.45) | KDM4EHSD17B10CACNA1BCASP1CACNA1C | |
| SCHEMBL8914182 | 0.84 | ALOX15 (0.53) | ALOX15KDM4EHSD17B10CACNA1CCYP2C9 | |
| SCHEMBL11683102 | 0.79 | KDM4E (0.59) | KDM4EHSD17B10CACNA1BCASP1CACNA1C | |
| SCHEMBL11781424 | 0.79 | ALOX15 (0.54) | ALOX15KDM4EHSD17B10CACNA1CCYP2C9 | |
| SCHEMBL7267980 | 0.78 | PYGL (0.61) | ALOX15KDM4ECACNA1CCYP2C9MEN1 | |
| SCHEMBL7410229 | 0.78 | CYP2C9 (0.66) | ALOX15KDM4EHSD17B10CACNA1CCYP2C9 | |
| SCHEMBL8912942 | 0.78 | CYP2C9 (0.58) | ALOX15KDM4EHSD17B10CACNA1BCACNA1C | |
| SCHEMBL3032376 | 0.78 | CYP2C9 (0.61) | ALOX15KDM4EHSD17B10CACNA1CCYP2C9 | |
| SCHEMBL11522526 | 0.78 | CYP2C9 (0.56) | ALOX15KDM4EHSD17B10CACNA1CCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066655-A | FOR THE TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS, IN PARTICULAR AS CEREBRAL THERAPEUTICS | BAYER AKTIENGESELLSCHAFT (DE) | 2000-05-23 | — | — | US | disclosed |
| US-5731333-A | LEARNING AND MEMORY ENHANCEMENT, ANTIDEPRESSANTS | BAYER AKTIENGESELLSCHAFT (DE) | 1998-03-24 | — | — | US | disclosed |