SCHEMBL80926

SCHEMBL80926

CC[Si](CC)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.41
PSIP1 O75475 1/20 0.35
TSHR P16473 3/20 0.33
LMNA P02545 2/20 0.33
ALOX12 P18054 2/20 0.33
ACHE P22303 1/20 0.33
TRPA1 O75762 1/20 0.32
ATM Q13315 1/20 0.32
KCNN4 O15554 1/20 0.32
HSD17B10 Q99714 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
CYP3A4 P08684 1/20 0.32
CALM1 P0DP23 1/20 0.32
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
LTA4H P09960 1/20 0.31
ALDH1A1 P00352 2/20 0.31
ALOX15 P16050 1/20 0.30
PTGS1 P23219 1/20 0.30
SLC6A2 P23975 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Fluoride SCHEMBL27660898 0.97 TP53 (0.39) TP53PSIP1TSHRLMNAALOX12
SCHEMBL8992243 0.83 LTA4H (0.36) TP53TSHRTDP1CES2CES1
SCHEMBL417806 0.78 TP53 (0.38) TP53PSIP1TSHRLMNAALOX12
SCHEMBL416584 0.77 TP53 (0.41) TP53PSIP1TSHRLMNAALOX12
SCHEMBL2229738 0.74 TP53 (0.39) TP53PSIP1TSHRLMNAALOX12
SCHEMBL417993 0.74 LTA4H (0.38) TP53TSHRTDP1CES2CES1
SCHEMBL418320 0.72 LTA4H (0.38) TP53CES2CES1LTA4HMAPK1
SCHEMBL9540158 0.72 TP53 (0.38) TP53PSIP1TSHRLMNAALOX12
SCHEMBL19200696 0.72 TP53 (0.38) TP53PSIP1TSHRLMNATRPA1
SCHEMBL28163890 0.72 MAPT (0.42) TP53TSHRLMNAACHEHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1062 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023070009-A1 SILYL ETHER DERIVATIVES OF POLYETHER POLYMERS P2 SCIENCE, INC. (US) 2023-04-27 WO claimed
CN-113683716-B Ethylene polymerization catalyst, preparation method thereof and preparation method of ethylene-isobutylene copolymer 中国石油天然气股份有限公司 2022-08-05 CN claimed
EP-3998304-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SmartKem Limited (GB) 2022-05-18 EP claimed
CN-113683716-A Ethylene polymerization catalyst, preparation method thereof and preparation method of ethylene-isobutylene copolymer 中国石油天然气股份有限公司 2021-11-23 CN claimed
EP-2817355-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-03-24 EP claimed
EP-2817356-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-02-17 EP claimed
EP-2817354-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2021-01-13 EP claimed
US-10833274-B2 Organic semiconductor compositions SMARTKEM LIMITED (GB) 2020-11-10 US claimed
EP-2817357-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-11-04 EP claimed
EP-2817351-B1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LTD (GB) 2020-08-26 EP claimed
WO-2013124682-A1 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
WO-2013124688-A2 ORGANIC SEMICONDUCTOR COMPOSITIONS SMARTKEM LIMITED (GB) 2013-08-29 WO claimed
US-7604874-B2 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM, LTD. (KR) 2009-10-20 US claimed
US-7485733-B2 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM, LTD. (KR) 2009-02-03 US claimed
US-20070037012-A1 having an anthracene compound substituted with at least one thiophenyl ring; OLED organic light emitters; as displays with low power consumption, faster response time, higher brightness level, unlimited viewing angle LG CHEM, LTD. (KR) 2007-02-15 US claimed
EP-1501821-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG Chem, Ltd. (KR) 2005-02-02 EP claimed
US-20040067387-A1 Organic compounds for electroluminescence and organic electroluminescent devices using the same LG CHEM. LTD. (KR) 2004-04-08 US claimed
WO-2003095445-A1 NEW ORGANIC COMPOUNDS FOR ELECTROLUMINESCENCE AND ORGANIC ELECTROLUMINESCENT DEVICES USING THE SAME LG CHEM, LTD. (KR) 2003-11-20 WO claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed