Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80926 | 0.72 | TP53 (0.41) | TP53PSIP1TSHRALDH1A1TRPA1 | |
| SCHEMBL416584 | 0.72 | TP53 (0.41) | TP53PSIP1TSHRALDH1A1TRPA1 | |
| SCHEMBL2229738 | 0.70 | TP53 (0.39) | TP53PSIP1TSHRTRPA1LMNA | |
| Fluoride SCHEMBL27660898 | 0.70 | TP53 (0.39) | TP53PSIP1TSHRTRPA1LMNA | |
| SCHEMBL3315510 | 0.69 | — | — | |
| SCHEMBL417806 | 0.68 | TP53 (0.38) | TP53PSIP1TSHRALDH1A1TRPA1 | |
| SCHEMBL19200696 | 0.68 | TP53 (0.38) | TP53PSIP1TSHRALDH1A1TRPA1 | |
| SCHEMBL27693684 | 0.68 | TP53 (0.38) | TP53PSIP1TSHRLMNAALOX12 | |
| SCHEMBL3666913 | 0.67 | — | — | |
| SCHEMBL5008947 | 0.67 | TSHR (0.39) | TSHRALDH1A1TRPA1LMNAALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0540580-A1 | POLYMERIC DRUG DELIVERY SYSTEM. | SEARLE & CO (US) | 1993-05-12 | — | — | EP | disclosed |