Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 6/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 10/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 8/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7566398 | 1.00 | ADORA1 (0.47) | ADORA1ADORA2AADORA2BADORA3CDK1 | |
| SCHEMBL7202952 | 0.90 | ADORA2A (0.57) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7207964 | 0.90 | ADORA2A (0.57) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7587828 | 0.90 | ADORA2A (0.57) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7208763 | 0.89 | CCNA2 (0.39) | ADORA2AADORA2BCDK5 | |
| SCHEMBL7574648 | 0.84 | ADORA2A (0.44) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7595823 | 0.84 | ADORA1 (0.48) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7567108 | 0.84 | ADORA2A (0.57) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7208885 | 0.83 | ADORA2A (0.38) | ADORA1ADORA2AADORA2BADORA3 | |
| SCHEMBL7202130 | 0.82 | ADORA2A (0.46) | ADORA2ACDK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056759-A1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999041267-A1 | 2-(PURIN-9-YL) -TETRAHYDROFURAN-3, 4-DIOL DERIVATIVES | GLAXO GROUP LIMITED (GB) | 1999-08-19 | — | — | WO | disclosed |