Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | THRA | P10827 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | TPMT | P51580 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809187 | 0.85 | ELANE (0.53) | PLA2G2AKMT2ATHRATHRBMEN1 | |
| SCHEMBL12693511 | 0.81 | KMT2A (0.56) | KMT2AELANEMAPTCA1CA2 | |
| SCHEMBL19473391 | 0.81 | PLA2G2A (0.41) | PLA2G2AKMT2ATHRATHRBMEN1 | |
| SCHEMBL22279621 | 0.81 | PLA2G2A (0.41) | PLA2G2AKMT2ATHRATHRBMEN1 | |
| SCHEMBL22941003 | 0.79 | KDM4E (0.37) | KMT2AMEN1ELANECA12CA1 | |
| SCHEMBL19480254 | 0.77 | ELANE (0.46) | PLA2G2AKMT2ATHRATHRBMEN1 | |
| SCHEMBL25845029 | 0.76 | HSD11B1 (0.33) | KMT2AMEN1ELANE | |
| SCHEMBL3686069 | 0.76 | ELANE (0.55) | KMT2AMEN1ELANEMAPTPKM | |
| SCHEMBL662703 | 0.75 | ELANE (0.53) | KMT2AMEN1ELANEMAPT | |
| SCHEMBL417129 | 0.74 | HSD17B10 (0.57) | PLA2G2AKMT2AMEN1ELANETPMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | disclosed |
| EP-1740629-B1 | PHOTOCHROMIC COMPOSITIONS AND ARTICLES COMPRISING SILOXANE, ALKYLENE OR SUBSTITUTED ALKYLENE OLIGOMERS | ADVANCED POLYMERIK PTY LTD (AU) | 2011-03-30 | — | — | EP | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| US-20090093601-A1 | Photochromic Compounds Comprising Polymeric Substituents And Methods For Preparation And Use Thereof | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2009-04-09 | — | — | US | disclosed |
| EP-1802726-A4 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LTD (AU) | 2008-04-30 | — | — | EP | disclosed |
| EP-1740629-A4 | PHOTOCHROMIC COMPOSITIONS AND ARTICLES COMPRISING SILOXANE, ALKYLENE OR SUBSTITUTED ALKYLENE OLIGOMERS | POLYMERS AUSTRALIA PTY LTD (AU) | 2007-10-24 | — | — | EP | disclosed |
| US-20070187656-A1 | Photochromic compositions and articles comprising siloxane, alkylene or substituted alkylene oligomers | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2007-08-16 | — | — | US | disclosed |
| US-20070187656-A1 | Photochromic compositions and articles comprising siloxane, alkylene or substituted alkylene oligomers | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2007-08-16 | — | — | US | disclosed |
| US-20070187656-A1 | Photochromic compositions and articles comprising siloxane, alkylene or substituted alkylene oligomers | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2007-08-16 | — | — | US | disclosed |
| EP-1802726-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | Polymers Australia PTY Limited (AU) | 2007-07-04 | — | — | EP | disclosed |
| EP-1740629-A1 | PHOTOCHROMIC COMPOSITIONS AND ARTICLES COMPRISING SILOXANE, ALKYLENE OR SUBSTITUTED ALKYLENE OLIGOMERS | Polymers Australia PTY Limited (AU) | 2007-01-10 | — | — | EP | disclosed |
| WO-2006024099-A1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2006-03-09 | — | — | WO | disclosed |
| WO-2005105875-A1 | PHOTOCHROMIC COMPOSITIONS AND ARTICLES COMPRISING SILOXANE, ALKYLENE OR SUBSTITUTED ALKYLENE OLIGOMERS | POLYMERS AUSTRALIA PTY LIMITED (AU) | 2005-11-10 | — | — | WO | disclosed |