SCHEMBL809305

SCHEMBL809305

CCCCO/C=C(\C)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.45
ATM Q13315 1/20 0.42
HCAR2 Q8TDS4 3/20 0.41
TSHR P16473 3/20 0.39
HPGD P15428 1/20 0.39
ACHE P22303 3/20 0.35
CES2 O00748 1/20 0.35
EP300 Q09472 1/20 0.35
THRB P10828 2/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
THRA P10827 1/20 0.34
ALOX15 P16050 1/20 0.33
AKR1B1 P15121 1/20 0.33
TP53 P04637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL809306 1.00 ALDH1A1 (0.45) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL28370469 0.98 ALDH1A1 (0.43) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL898727 0.94 HCAR2 (0.43) ALDH1A1ATMHCAR2TSHRACHE
SCHEMBL898728 0.94 HCAR2 (0.43) ALDH1A1ATMHCAR2TSHRACHE
SCHEMBL28126163 0.92 CES2 (0.46) ALDH1A1HCAR2TSHRACHECES2
SCHEMBL3388405 0.92 CES2 (0.46) ALDH1A1HCAR2TSHRACHECES2
Acrylamide SCHEMBL28247682 0.88 TSHR (0.43) ALDH1A1ATMHCAR2TSHRHPGD
SCHEMBL2219163 0.87 HCAR2 (0.38) ALDH1A1ATMHCAR2
SCHEMBL2219157 0.87 HCAR2 (0.38) ALDH1A1ATMHCAR2
Glycolic Acid SCHEMBL10531852 0.86 CES2 (0.41) ALDH1A1HCAR2TSHRCES2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1802726-B1 PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF ADVANCED POLYMERIK PTY LTD (AU) 2011-11-30 EP claimed