Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 4/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 1/20 | 0.37 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.37 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.37 |
| ▸ | BLM | P54132 | 2/20 | 0.37 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898554 | 0.94 | HCAR2 (0.55) | HCAR2ATMCES2PTPN1 | |
| SCHEMBL11339872 | 0.94 | HCAR2 (0.55) | HCAR2ATMCES2PTPN1 | |
| SCHEMBL15750729 | 0.88 | HCAR2 (0.50) | HCAR2ATMTSHRPTPN1GABRR1 | |
| SCHEMBL12965631 | 0.87 | HCAR2 (0.49) | HCAR2ATMTSHRALDH1A1PTPN1 | |
| SCHEMBL17884756 | 0.84 | ATM (0.45) | HCAR2ATMTSHRALDH1A1CES2 | |
| Maleic Acid SCHEMBL12981050 | 0.83 | HCAR2 (0.67) | HCAR2ATMTSHRALDH1A1CES2 | |
| Fumaric Acid SCHEMBL5935166 | 0.83 | HCAR2 (0.67) | HCAR2ATMTSHRALDH1A1CES2 | |
| SCHEMBL10947653 | 0.82 | ATM (0.44) | HCAR2ATMTSHRALDH1A1CES2 | |
| Glutaconate SCHEMBL31023345 | 0.81 | HCAR2 (0.50) | HCAR2ATMTSHRALDH1A1CES2 | |
| SCHEMBL712631 | 0.81 | ATM (0.68) | HCAR2ATMTSHRALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802726-B1 | PHOTOCHROMIC COMPOUNDS COMPRISING POLYMERIC SUBSTITUENTS AND METHODS FOR PREPARATION AND USE THEREOF | ADVANCED POLYMERIK PTY LTD (AU) | 2011-11-30 | — | — | EP | claimed |