Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.78 |
| ▸ | PTGS1 | P23219 | 7/20 | 0.78 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8094216 | 0.89 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL8093929 | 0.88 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8098606 | 0.86 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL8098732 | 0.85 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL8095458 | 0.84 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL8094071 | 0.83 | PTGS2 (0.80) | PTGS2PTGS1 | |
| SCHEMBL8098062 | 0.83 | PTGS2 (0.76) | PTGS2PTGS1 | |
| Hydrochloric Acid SCHEMBL8098724 | 0.82 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL8093964 | 0.82 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL8098057 | 0.82 | PTGS2 (0.75) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |
| US-5686470-A | 2, 3-substituted pyridines for the treatment of inflammation | WEIER RICHARD M (US) | 1997-11-11 | — | — | US | disclosed |