Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 18/20 | 0.75 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.75 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8098062 | 0.99 | PTGS2 (0.76) | PTGS2PTGS1LTB4RLTB4R2 | |
| SCHEMBL8094137 | 0.91 | PTGS2 (0.64) | PTGS2PTGS1LTB4RLTB4R2 | |
| SCHEMBL8093929 | 0.86 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL8093962 | 0.85 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL8092516 | 0.84 | PTGS2 (0.65) | PTGS2PTGS1 | |
| SCHEMBL8098732 | 0.83 | PTGS2 (0.83) | PTGS2PTGS1 | |
| SCHEMBL8098606 | 0.83 | PTGS2 (0.79) | PTGS2PTGS1 | |
| SCHEMBL8098057 | 0.82 | PTGS2 (0.75) | PTGS2PTGS1 | |
| SCHEMBL8095458 | 0.82 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL8093124 | 0.82 | PTGS2 (0.78) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0808304-B1 | 2,3-SUBSTITUTED PYRIDINES FOR THE TREATMENT OF INFLAMMATION | SEARLE & CO (US) | 2000-12-27 | — | — | EP | disclosed |