Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 1.00 |
| ▸ | HPGD | P15428 | 5/20 | 1.00 |
| ▸ | RAB9A | P51151 | 4/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 1.00 |
| ▸ | GABRP | O00591 | 6/20 | 0.71 |
| ▸ | GABRD | O14764 | 6/20 | 0.71 |
| ▸ | GABRA1 | P14867 | 6/20 | 0.71 |
| ▸ | GABRB1 | P18505 | 6/20 | 0.71 |
| ▸ | GABRG2 | P18507 | 6/20 | 0.71 |
| ▸ | GABRB3 | P28472 | 6/20 | 0.71 |
| ▸ | GABRA5 | P31644 | 6/20 | 0.71 |
| ▸ | GABRA3 | P34903 | 6/20 | 0.71 |
| ▸ | GABRA2 | P47869 | 6/20 | 0.71 |
| ▸ | GABRB2 | P47870 | 6/20 | 0.71 |
| ▸ | GABRA4 | P48169 | 6/20 | 0.71 |
| ▸ | GABRE | P78334 | 6/20 | 0.71 |
| ▸ | GABRA6 | Q16445 | 6/20 | 0.71 |
| ▸ | GABRG1 | Q8N1C3 | 6/20 | 0.71 |
| ▸ | GABRG3 | Q99928 | 6/20 | 0.71 |
| ▸ | GABRQ | Q9UN88 | 6/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4634256 | 0.85 | HPGD (0.73) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL17786454 | 0.83 | NPC1 (0.71) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL311588 | 0.83 | HPGD (0.76) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL8025501 | 0.80 | HPGD (0.67) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL2436664 | 0.80 | HPGD (0.67) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL25186939 | 0.80 | HPGD (0.67) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL87773 | 0.80 | HPGD (0.67) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL530293 | 0.80 | HPGD (0.67) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL312255 | 0.80 | AKR1C3 (1.00) | NPC1HPGDRAB9ASMN1; SMN2GABRP | |
| SCHEMBL3205778 | 0.80 | HPGD (0.67) | NPC1HPGDRAB9ASMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399584-A | Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-21 | — | — | US | claimed |
| US-6046231-A | ADMINISTERING A SUFFICIENT AMOUNT OF A CANCER CHEMOPREVENTATIVE COMPOSITION COMPRISING 4'-BROMOFLAVONE TO A MAMMAL IN NEED TO PREVENT, DELAY OR REVERSE A CANCER SENSITIVE TO 4'-BROMOFLAVONE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 2000-04-04 | — | — | US | disclosed |
| US-5399584-A | Preventing gastrointestinal damage caused by nonsteroidal antiinflammatory drugs | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-21 | — | — | US | disclosed |