Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | ANPEP | P15144 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | HTR1B | P28222 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7088869 | 0.81 | TAAR1 (0.31) | ALDH1A1CYP2A6TDP1TSHRHSD17B10 | |
| SCHEMBL15972458 | 0.79 | DNMT1 (0.39) | ALDH1A1TDP1KDM4ELMNAGAA | |
| SCHEMBL1933967 | 0.79 | DNMT1 (0.39) | ALDH1A1TDP1KDM4ELMNAGAA | |
| SCHEMBL5698110 | 0.78 | ALDH1A1 (0.43) | ALDH1A1CYP2A6CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL14809988 | 0.75 | CYBB (0.33) | ALDH1A1CYP1A2CYP2C19CYP2D6TSHR | |
| SCHEMBL15660328 | 0.74 | ALDH1A1 (0.40) | ALDH1A1CYP2A6CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL17529811 | 0.74 | ACHE (0.38) | ALDH1A1ANPEPCYP1A2CYP2D6TSHR | |
| SCHEMBL11125316 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CYP2A6CYP1A2CYP2C19CYP2D6 | |
| SCHEMBL30568731 | 0.74 | ALDH1A1 (0.43) | ALDH1A1CYP2A6CYP1A2CYP2C19TDP1 | |
| SCHEMBL7033231 | 0.72 | ANPEP (0.37) | ALDH1A1ANPEPGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0732336-B1 | Process for the preparation of arylalkyl phosphines, arylalkyl phosphine oxides or arylalkyl phosphine sulfides | CYTEC CANADA INC (CA) | 2000-12-20 | — | — | EP | disclosed |
| EP-0732336-A1 | Process for the preparation of arylalkyl phosphines, arylalkyl phosphine oxides or arylalkyl phosphine sulfides | Cytec Canada Inc. (CA) | 1996-09-18 | — | — | EP | disclosed |
| US-5550295-A | Preparation of arylalkyl phosphines, phosphine oxides or phosphine sulfides | CYTEC TECHNOLOGY CORP. (US) | 1996-08-27 | — | — | US | disclosed |