Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | EBP | Q15125 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8100525 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL8099732 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL8095795 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL28018267 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL8100094 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL8095635 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL8087655 | 1.00 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL827203 | 0.98 | SIGMAR1 (0.41) | SIGMAR1EBPCNR2CNR1GAA | |
| SCHEMBL1719930 | 0.91 | KIF11 (0.41) | SIGMAR1TAAR1MEN1KMT2ACYP2D6 | |
| SCHEMBL27706716 | 0.89 | ESR1 (0.52) | CNR2CNR1CYP2C9CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |